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The quest for genetic determinants of human longevity: challenges and insights

Twin studies show that genetic differences account for about a quarter of the variance in adult human lifespan. Common polymorphisms that have a modest effect on lifespan have been identified in one gene, APOE, providing hope that other genetic determinants can be uncovered. However, although varian...

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Main Authors: Christensen, Kaare, Johnson, Thomas E., Vaupel, James W.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726954/
https://ncbi.nlm.nih.gov/pubmed/16708071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg1871
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