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Growth Hormone, Insulin-Like Growth Factors, and the Skeleton

GH and IGF-I are important regulators of bone homeostasis and are central to the achievement of normal longitudinal bone growth and bone mass. Although GH may act directly on skeletal cells, most of its effects are mediated by IGF-I, which is present in the systemic circulation and is synthesized by...

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Detalhes bibliográficos
Main Authors: Giustina, Andrea, Mazziotti, Gherardo, Canalis, Ernesto
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726838/
https://ncbi.nlm.nih.gov/pubmed/18436706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/er.2007-0036
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