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Use of Disulfide “Staples” to Stabilize β-Sheet Quaternary Structure

[Image: see text] This letter reports the use of disulfide linkages to stabilize a β-sheet dimer with a well-defined structure in aqueous and dimethyl sulfoxide solutions. In this dimer, two cyclic β-sheet peptides are connected by disulfide linkages at the non-hydrogen-bonded rings. The cyclic β-sh...

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Detalles Bibliográficos
Main Authors: Khakshoor, Omid, Nowick, James S.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726807/
https://ncbi.nlm.nih.gov/pubmed/19534505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol901015a
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