IMMUNOGENICITY OF HUMAN MESENCHYMAL STEM CELLS IN HLA-CLASS I RESTRICTED T CELL RESPONSES AGAINST VIRAL OR TUMOR-ASSOCIATED ANTIGENS

Human mesenchymal stem cells (MSC) are immunosuppressive and poorly immunogenic, but may act as antigen-presenting cells (APC) for CD4(+) T cell responses; here we have investigated their ability to serve as APC for in vitro CD8(+) T cell responses. MSC pulsed with peptides from viral antigens evoke...

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Detalhes bibliográficos
Main Authors: Morandi, Fabio, Raffaghello, Lizzia, Bianchi, Giovanna, Meloni, Francesca, Salis, Annalisa, Millo, Enrico, Ferrone, Soldano, Barnaba, Vincenzo, Pistoia, Vito
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726787/
https://ncbi.nlm.nih.gov/pubmed/18292209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2007-0878
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