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Bdnf Overexpression in Hippocampal Neurons Prevents Dendritic Atrophy Caused by Rett-Associated MECP2 Mutations

The expression of the methylated DNA-binding protein MeCP2 increases during neuronal development, which suggests that this epigenetic factor is crucial for neuronal terminal differentiation. We evaluated dendritic and axonal development in embryonic day-18 hippocampal neurons in culture by measuring...

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Hlavní autoři: Larimore, Jennifer L., Chapleau, Christopher A., Kudo, Shinichi, Theibert, Anne, Percy, Alan K., Pozzo-Miller, Lucas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726722/
https://ncbi.nlm.nih.gov/pubmed/19217433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.12.011
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