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Connective tissue growth factor hammerhead ribozyme attenuates human hepatic stellate cell function

AIM: To determine the effect of hammerhead ribozyme targeting connective tissue growth factor (CCN2) on human hepatic stellate cell (HSC) function. METHODS: CCN2 hammerhead ribozyme cDNA plus two self-cleaving sequences were inserted into pTriEx2 to produce pTriCCN2-Rz. Each vector was individually...

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Hlavní autoři: Gao, Run-Ping, Brigstock, David R
Médium: Artigo
Jazyk:Inglês
Vydáno: The WJG Press and Baishideng 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726461/
https://ncbi.nlm.nih.gov/pubmed/19673024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.15.3807
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