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Inhibitory Effect of Flavonoids on the Efflux of N-Acetyl 5-Aminosalicylic Acid Intracellularly Formed in Caco-2 Cells

N-acetyl 5-aminosalicylic acid (5-AcASA) that was intracellularly formed from 5-aminosalicylic acid (5-ASA) at 200 μM was discharged 5.3, 7.1, and 8.1-fold higher into the apical site than into the basolateral site during 1, 2, and 4-hour incubations, respectively, in Caco-2 cells grown in Transwell...

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Detalhes bibliográficos
Main Authors: Shin, Yoshimura, Kentaro, Kawano, Ryusuke, Matsumura, Narumi, Sugihara, Koji, Furuno
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726441/
https://ncbi.nlm.nih.gov/pubmed/19688110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/467489
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