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Darwinian selection for sites of Asn-linked glycosylation in phylogenetically disparate eukaryotes and viruses

Numerous protists and rare fungi have truncated Asn-linked glycan precursors and lack N-glycan-dependent quality control (QC) systems for glycoprotein folding in the endoplasmic reticulum. Here, we show that the abundance of sequons (NXT or NXS), which are sites for N-glycosylation of secreted and m...

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Detalhes bibliográficos
Main Authors: Cui, Jike, Smith, Temple, Robbins, Phillips W., Samuelson, John
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726397/
https://ncbi.nlm.nih.gov/pubmed/19666543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905818106
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