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DNA-mediated redox signaling for transcriptional activation of SoxR

In enteric bacteria, the cellular response to oxidative stress is activated by oxidation of the iron-sulfur clusters in SoxR, which then induces transcription of soxS, turning on a battery of defense genes. Here we demonstrate both in vitro and in cells that activation of SoxR can occur in a DNA-med...

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Detalhes bibliográficos
Main Authors: Lee, Paul E., Demple, Bruce, Barton, Jacqueline K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726364/
https://ncbi.nlm.nih.gov/pubmed/19651620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906429106
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