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Activation of the Aryl Hydrocarbon Receptor during Different Critical Windows in Pregnancy Alters Mammary Epithelial Cell Proliferation and Differentiation

Exposure to the aryl hydrocarbon receptor (AhR) agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) during pregnancy causes severe defects in mammary gland development and function; however, the underlying mechanism remains unclear. Alterations in epithelial cell proliferation, differentiation, and a...

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Detalhes bibliográficos
Main Authors: Lew, Betina J., Collins, Loretta L., O'Reilly, Michael A., Lawrence, B. Paige
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726296/
https://ncbi.nlm.nih.gov/pubmed/19502548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp125
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