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Long-term pegylated interferon-α and its potential in the treatment of melanoma

Conventional interferons including interferon-α (IFN-α) are cytokines used for years in the treatment of solid tumors and hematological malignancies. Their half-life is short. Pegylated forms of IFN-α present an improved pharmacokinetic profile that rendered them the preferred IFNs in hepatitis ther...

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Detalhes bibliográficos
Main Authors: Dummer, Reinhard, Mangana, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726079/
https://ncbi.nlm.nih.gov/pubmed/19707406
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