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Bosentan in the treatment of pulmonary arterial hypertension with the focus on the mildly symptomatic patient

Pulmonary arterial hypertension (PAH) is a progressive disease with poor survival outcomes. Bosentan is an oral endothelin-1 receptor antagonist (ERA) that has been shown in a large randomized placebo-controlled trial (BREATHE-1) to be effective at improving exercise tolerance in patients with PAH i...

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Autores principales: Valerio, Christopher J, Coghlan, John G
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725793/
https://ncbi.nlm.nih.gov/pubmed/19688101
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