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Towards a rational approach for heavy-atom derivative screening in protein crystallography

Heavy-atom derivatization is routinely used in protein structure determination and is thus of critical importance in structural biology. In order to replace the current trial-and-error heavy-atom derivative screening with a knowledge-based rational derivative-selection method, the reactivity of more...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Agniswamy, Johnson, Joyce, M. Gordon, Hammer, Carl H., Sun, Peter D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725783/
https://ncbi.nlm.nih.gov/pubmed/18391402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444907068849
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