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MLL Associates with Telomeres and Regulates Telomeric Repeat-Containing RNA Transcription

Mammalian telomeres consist of TTAGGG repeats organized in nucleosomes and associated with a six-protein complex known as shelterin, which preserves telomere structure and protects chromosome ends from the cellular DNA damage response. Recent studies have found that telomeres are transcribed into te...

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Bibliographic Details
Main Authors: Caslini, Corrado, Connelly, James A., Serna, Amparo, Broccoli, Dominique, Hess, Jay L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725733/
https://ncbi.nlm.nih.gov/pubmed/19528237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00195-09
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