Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue

Adipose tissue can undergo rapid expansion during times of excess caloric intake. Like a rapidly expanding tumor mass, obese adipose tissue becomes hypoxic due to the inability of the vasculature to keep pace with tissue growth. Consequently, during the early stages of obesity, hypoxic conditions ca...

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Detalhes bibliográficos
Main Authors: Halberg, Nils, Khan, Tayeba, Trujillo, Maria E., Wernstedt-Asterholm, Ingrid, Attie, Alan D., Sherwani, Shariq, Wang, Zhao V., Landskroner-Eiger, Shira, Dineen, Sean, Magalang, Ulysses J., Brekken, Rolf A., Scherer, Philipp E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725728/
https://ncbi.nlm.nih.gov/pubmed/19546236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00192-09
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