The Alternative TrkAIII Splice Variant Targets the Centrosome and Promotes Genetic Instability

The hypoxia-regulated alternative TrkAIII splice variant expressed by human neuroblastomas exhibits oncogenic potential, driven by in-frame exon 6 and 7 alternative splicing, leading to omission of the receptor extracellular immunoglobulin C(1) domain and several N-glycosylation sites. Here, we show...

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Autores principales: Farina, Antonietta Rosella, Tacconelli, Antonella, Cappabianca, Lucia, Cea, Gesilia, Panella, Sonia, Chioda, Antonella, Romanelli, Alessandra, Pedone, Carlo, Gulino, Alberto, Mackay, Andrew Reay
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725721/
https://ncbi.nlm.nih.gov/pubmed/19564412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00352-09
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