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The Alternative TrkAIII Splice Variant Targets the Centrosome and Promotes Genetic Instability
The hypoxia-regulated alternative TrkAIII splice variant expressed by human neuroblastomas exhibits oncogenic potential, driven by in-frame exon 6 and 7 alternative splicing, leading to omission of the receptor extracellular immunoglobulin C(1) domain and several N-glycosylation sites. Here, we show...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2725721/ https://ncbi.nlm.nih.gov/pubmed/19564412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00352-09 |
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