CsrRS Regulates Group B Streptococcus Virulence Gene Expression in Response to Environmental pH: a New Perspective on Vaccine Development

To identify factors involved in the response of group B streptococci (GBS) to environmental pH, we performed a comparative global gene expression analysis of GBS at acidic and neutral pHs. We found that the transcription of 317 genes was increased at pH 5.5 relative to that at pH 7.0, while 61 genes...

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Autors principals: Santi, Isabella, Grifantini, Renata, Jiang, Sheng-Mei, Brettoni, Cecilia, Grandi, Guido, Wessels, Michael R., Soriani, Marco
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Molecular Biology of Pathogens
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725634/
https://ncbi.nlm.nih.gov/pubmed/19542277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00370-09
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