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An A257V Mutation in the Bacillus subtilis Response Regulator Spo0A Prevents Regulated Expression of Promoters with Low-Consensus Binding Sites

In Bacillus species, the master regulator of sporulation is Spo0A. Spo0A functions by both activating and repressing transcription initiation from target promoters that contain 0A boxes, the binding sites for Spo0A. Several classes of spo0A mutants have been isolated, and the molecular basis for the...

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Detalhes bibliográficos
Main Authors: Seredick, Steve D., Seredick, Barbara M., Baker, David, Spiegelman, George B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725607/
https://ncbi.nlm.nih.gov/pubmed/19581368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00590-09
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