Phase I Safety and Immunogenicity Study of a Candidate Meningococcal Disease Vaccine Based on Neisseria lactamica Outer Membrane Vesicles

Natural immunity to meningococcal disease in young children is associated epidemiologically with carriage of commensal Neisseria species, including Neisseria lactamica. We have previously demonstrated that outer membrane vesicles (OMVs) from N. lactamica provide protection against lethal challenge i...

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Bibliographische Detailangaben
Hauptverfasser: Gorringe, Andrew R., Taylor, Stephen, Brookes, Charlotte, Matheson, Mary, Finney, Michelle, Kerr, Moyra, Hudson, Michael, Findlow, Jamie, Borrow, Ray, Andrews, Nick, Kafatos, George, Evans, Cariad M., Read, Robert C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Vaccine Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725532/
https://ncbi.nlm.nih.gov/pubmed/19553555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00118-09
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