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AAV-mediated local delivery of interferon-β for the treatment of retinoblastoma in preclinical models
Interferon-β (IFN-β has been found to have anti-tumor properties against a variety of malignancies through different mechanisms. However, clinical trials involving systemic administration of IFN-β have been hampered by secondary toxicity and the short half-life of IFN-β in the circulation. In order...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2725441/ https://ncbi.nlm.nih.gov/pubmed/19306089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12017-009-8059-0 |
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