Identification of a Domain which Affects Kinetics and Antagonistic Potency of Clozapine at 5-HT(3) Receptors

The widely used atypical antipsychotic clozapine is a potent competitive antagonist at 5-HT(3) receptors which may contribute to its unique psychopharmacological profile. Clozapine binds to 5-HT(3) receptors of various species. However, the structural requirements of the respective binding site for...

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Detaylı Bibliyografya
Asıl Yazarlar: Rammes, Gerhard, Hosp, Christine, Eisensamer, Brigitte, Tanasic, Sascha, Nothdurfter, Caroline, Zieglgänsberger, Walter, Rupprecht, Rainer
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2009
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725292/
https://ncbi.nlm.nih.gov/pubmed/19696922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006715
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