Complex Oncogenic Translocations with Gene Amplification are Initiated by Specific DNA Breaks in Lymphocytes

Chromosomal instability is a hallmark of many tumor types. Complex chromosomal rearrangements with associated gene amplification, known as complicons, characterize many hematologic and solid cancers. While chromosomal aberrations, including complicons, are useful diagnostic and prognostic cancer mar...

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Detalhes bibliográficos
Main Authors: Wright, Sarah M., Woo, Yong H., Alley, Travis L., Shirley, Bobbi-Jo, Akeson, Ellen C., Snow, Kathy J., Maas, Sarah A., Elwell, Rachel L., Foreman, Oded, Mills, Kevin D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724672/
https://ncbi.nlm.nih.gov/pubmed/19435904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4515
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