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Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma
BACKGROUND: Glucocorticoid function is dependent on efficient translocation of the glucocorticoid receptor (GR) from the cytoplasm to the nucleus of cells. Importin-13 (IPO13) is a nuclear transport receptor that mediates nuclear entry of GR. In airway epithelial cells, inhibition of IPO13 expressio...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724419/ https://ncbi.nlm.nih.gov/pubmed/19619331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-10-67 |
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