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A physical and functional link between splicing factors promotes pre-mRNA 3′ end processing

Polypyrimidine tract-binding protein (PTB) is a splicing regulator that also plays a positive role in pre-mRNA 3′ end processing when bound upstream of the polyadenylation signal (pA signal). Here, we address the mechanism of PTB stimulatory function in mRNA 3′ end formation. We identify PTB as the...

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Detalhes bibliográficos
Main Authors: Millevoi, Stefania, Decorsière, Adrien, Loulergue, Clarisse, Iacovoni, Jason, Bernat, Sandra, Antoniou, Michael, Vagner, Stéphan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724285/
https://ncbi.nlm.nih.gov/pubmed/19506027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp470
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