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Adipocyte-derived factor reduces vasodilatory capability in ob(−)/ob(−) mice

Obesity is associated with impaired functional hyperemic response. We have shown that ATP-sensitive potassium (K(ATP)) channels are important in mediating functional vasodilation. Adipocyte-derived factors (ADFs) can alter vascular tone via opening K(ATP) channels. We hypothesize that, in an animal...

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Detalhes bibliográficos
Main Authors: Xiang, Lusha, Hester, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724221/
https://ncbi.nlm.nih.gov/pubmed/19502550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01327.2008
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