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Molecular mechanism underlying Akt activation in zinc-induced cardioprotection
Our previous study demonstrated that zinc prevents cardiac reperfusion injury by targeting the mitochondrial permeability transition pore (mPTP) via Akt and glycogen synthetase kinase 3β (GSK-3β). We aimed to address the mechanism by which zinc activates Akt. Treatment of H9c2 cells with ZnCl(2) (10...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724202/ https://ncbi.nlm.nih.gov/pubmed/19525380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00293.2009 |
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