Role of γ-glutamyl transpeptidase in redox regulation of K(+) channel remodeling in postmyocardial infarction rat hearts

γ-Glutamyl transpeptidase (γ-GT) is a key enzyme in GSH metabolism that regulates intracellular GSH levels in response to extracellular GSH (GSH(o)). The objective of this study was to identify the role of γ-GT in reversing pathogenic K(+) channel remodeling in the diseased heart. Chronic ventricula...

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Hlavní autoři: Zheng, Ming-Qi, Tang, Kang, Zimmerman, Matthew C., Liu, Liping, Xie, Bin, Rozanski, George J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2009
Témata:
Membrane Transporters, Ion Channels, and Pumps
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724099/
https://ncbi.nlm.nih.gov/pubmed/19419996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00634.2008
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