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Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of Pseudomonas aeruginosa

Patients with cystic fibrosis (CF) exhibit defective innate immunity and are susceptible to chronic lung infection with Pseudomonas aeruginosa. To investigate the molecular bases for the hypersusceptibility of CF patients to P. aeruginosa, we used the IB3-1 cell line with two defective CF transmembr...

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Main Authors: Bajmoczi, Milan, Gadjeva, Mihaela, Alper, Seth L., Pier, Gerald B., Golan, David E.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724095/
https://ncbi.nlm.nih.gov/pubmed/19386787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00527.2008
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