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Acetyl-CoA Carboxylase-α Inhibitor TOFA Induces Human Cancer Cell Apoptosis

Acetyl-CoA carboxylase-α (ACCA) is a rate-limiting enzyme in long chain fatty acid synthesis, playing a critical role in cellular energy storage and lipid synthesis. ACCA is upregulated in multiple types of human cancers and small interfering RNA-mediated ACCA silencing in human breast and prostate...

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Detalhes bibliográficos
Main Authors: Wang, Chun, Xu, Canxin, Sun, Mingwei, Luo, Dixian, Liao, Duan-fang, Cao, Deliang
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724073/
https://ncbi.nlm.nih.gov/pubmed/19450551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.05.045
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