Complement Inhibitor Eculizumab in Atypical Hemolytic Uremic Syndrome

Background and objectives: Atypical hemolytic uremic syndrome (aHUS) is associated with a congenital or acquired dysregulation of the complement alternative pathway that leads to continuous complement activation on host cells causing inflammation and damage. Eculizumab, a humanized mAb against compl...

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Detalhes bibliográficos
Main Authors: Mache, Christoph J., Acham-Roschitz, Birgit, Frémeaux-Bacchi, Veronique, Kirschfink, Michael, Zipfel, Peter F., Roedl, Siegfried, Vester, Udo, Ring, Ekkehard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2009
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723971/
https://ncbi.nlm.nih.gov/pubmed/19556379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.01090209
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