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Genetic Diversity of the Malaria Vaccine Candidate Plasmodium falciparum Merozoite Surface Protein-3 in a Hypoendemic Transmission Environment

The N-terminal domain of Plasmodium falciparum merozoite surface protein-3 (PfMSP3) has been excluded from malaria vaccine development largely because of genetic diversity concerns. However, no study to date has followed N-terminal diversity over time. This study describes PfMSP3 variation in a hypo...

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Detalhes bibliográficos
Main Authors: Jordan, Stephen J., Branch, OraLee H., Castro, Jean Carlos, Oster, Robert A., Rayner, Julian C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723947/
https://ncbi.nlm.nih.gov/pubmed/19270302
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