A Core MYC Gene Expression Signature Is Prominent in Basal-Like Breast Cancer but Only Partially Overlaps the Core Serum Response

BACKGROUND: The MYC oncogene contributes to induction and growth of many cancers but the full spectrum of the MYC transcriptional response remains unclear. METHODOLOGY/PRINCIPAL FINDINGS: Using microarrays, we conducted a detailed kinetic study of genes that respond to MYCN or MYCNΔMBII induction in...

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Detalhes bibliográficos
Main Authors: Chandriani, Sanjay, Frengen, Eirik, Cowling, Victoria H., Pendergrass, Sarah A., Perou, Charles M., Whitfield, Michael L., Cole, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723908/
https://ncbi.nlm.nih.gov/pubmed/19690609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006693
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