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Macrocyclic Design Strategies for Small, Stable Parallel β-Sheet Scaffolds
[Image: see text] Pairs of short peptide strands can be induced to adopt antiparallel β-sheet secondary structure in aqueous solution via a macrocyclic constraint, as illustrated by many natural and designed peptides. We show that an analogous strategy is successful for creation of small units of pa...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2723809/ https://ncbi.nlm.nih.gov/pubmed/19456161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja902210f |
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