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Macrocyclic Design Strategies for Small, Stable Parallel β-Sheet Scaffolds

[Image: see text] Pairs of short peptide strands can be induced to adopt antiparallel β-sheet secondary structure in aqueous solution via a macrocyclic constraint, as illustrated by many natural and designed peptides. We show that an analogous strategy is successful for creation of small units of pa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Freire, Felix, Gellman, Samuel H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723809/
https://ncbi.nlm.nih.gov/pubmed/19456161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja902210f
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