ABCB1 genetic variation influences the toxicity and clinical outcome of patients with androgen independent prostate cancer treated with docetaxel

PURPOSE: Polymorphisms that are associated with ABCB1 expression and function may be linked to treatment efficacy and the development of neutropenia and neurotoxicity in patients with androgen independent prostate cancer (AIPC) receiving docetaxel. EXPERIMENTAL DESIGN: Patients with AIPC treated wit...

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Main Authors: Sissung, Tristan M., Baum, Caitlin E., Deeken, John, Price, Douglas K., Aragon-Ching, Jeanny, Steinberg, Seth M., Dahut, William, Sparreboom, Alex, Figg, William D.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723795/
https://ncbi.nlm.nih.gov/pubmed/18628469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4230
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