Delivery to the lower respiratory tract is required for effective immunization with Newcastle disease virus-vectored vaccines intended for humans

Newcastle disease virus (NDV), an avian virus, is being evaluated for the development of vectored human vaccines against emerging pathogens. Previous studies of NDV-vectored vaccines in a mouse model suggested their potency after delivery by injection or by the intranasal route. We compared the effi...

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Autori principali: DiNapoli, Joshua M., Ward, Jerrold M., Cheng, Lily, Yang, Lijuan, Elankumaran, Subbiah, Murphy, Brian R., Samal, Siba K., Collins, Peter L., Bukreyev, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Science 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723768/
https://ncbi.nlm.nih.gov/pubmed/19168110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.01.009
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