Lung NF-κB Activation and Neutrophil Recruitment Require IL-1 and TNF Receptor Signaling during Pneumococcal Pneumonia

Pulmonary inflammation is an essential component of the host defense against Streptococcus pneumoniae infection of the lungs. The early response cytokines, TNF-α and IL-1, are rapidly induced upon microbial exposure. Mice deficient in all TNF- and IL-1-dependent signaling receptors were used to dete...

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Bibliographic Details
Main Authors: Jones, Matthew R., Simms, Benjamin T., Lupa, Michal M., Kogan, Mariya S., Mizgerd, Joseph P.
Format: Artigo
Language:Inglês
Published: 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723739/
https://ncbi.nlm.nih.gov/pubmed/16301661
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