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Role of CD44 in the differentiation of Th1 and Th2 cells: CD44-deficiency enhances the development of Th2 effectors in response to SRBC and chicken ovalbumin

CD4 T cells can be primarily polarized to differentiate into Th1 or Th2 cells. CD44 is a marker of T cell activation and a property of long-lived memory cells and implicated in cell migration, activation and differentiation. To date, whether CD44 has a role in regulating Th1-Th2 differentiation has...

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Autors principals: Guan, Hongbing, Nagarkatti, Prakash S., Nagarkatti, Mitzi
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723169/
https://ncbi.nlm.nih.gov/pubmed/19542428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802325
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