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Inactivation of the C. elegans lipin homolog leads to ER disorganization and to defects in the breakdown and reassembly of the nuclear envelope

The nuclear envelope (NE) is a dynamic structure, undergoing periods of growth, breakdown and reassembly during the cell cycle. In yeast, altering lipid synthesis by inactivating the yeast homolog of lipin, a phosphatidic acid phosphohydrolase, leads to disorganization of the peripheral ER and abnor...

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Detalhes bibliográficos
Main Authors: Golden, Andy, Liu, Jun, Cohen-Fix, Orna
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723152/
https://ncbi.nlm.nih.gov/pubmed/19494126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.044743
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