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Decay of linkage disequilibrium within genes across HGDP-CEPH human samples: most population isolates do not show increased LD

BACKGROUND: It is well known that the pattern of linkage disequilibrium varies between human populations, with remarkable geographical stratification. Indirect association studies routinely exploit linkage disequilibrium around genes, particularly in isolated populations where it is assumed to be hi...

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Detalhes bibliográficos
Main Authors: Bosch, Elena, Laayouni, Hafid, Morcillo-Suarez, Carlos, Casals, Ferran, Moreno-Estrada, Andrés, Ferrer-Admetlla, Anna, Gardner, Michelle, Rosa, Araceli, Navarro, Arcadi, Comas, David, Graffelman, Jan, Calafell, Francesc, Bertranpetit, Jaume
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723139/
https://ncbi.nlm.nih.gov/pubmed/19638193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-338
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