Decay of linkage disequilibrium within genes across HGDP-CEPH human samples: most population isolates do not show increased LD

BACKGROUND: It is well known that the pattern of linkage disequilibrium varies between human populations, with remarkable geographical stratification. Indirect association studies routinely exploit linkage disequilibrium around genes, particularly in isolated populations where it is assumed to be hi...

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Main Authors: Bosch, Elena, Laayouni, Hafid, Morcillo-Suarez, Carlos, Casals, Ferran, Moreno-Estrada, Andrés, Ferrer-Admetlla, Anna, Gardner, Michelle, Rosa, Araceli, Navarro, Arcadi, Comas, David, Graffelman, Jan, Calafell, Francesc, Bertranpetit, Jaume
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723139/
https://ncbi.nlm.nih.gov/pubmed/19638193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-338
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