Simultaneous Foxp3 and IDO expression is associated with sentinel lymph node metastases in breast cancer

BACKGROUND: There is evidence that the immune systems of patients with breast cancer are dysfunctional. Regulatory T cells (Tregs), and IDO, an immunosuppressive enzyme, are associated with more advanced disease in some cancers and may promote immunologic tolerance to tumors. Our aim was to assess w...

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Главные авторы: Mansfield, Aaron S, Heikkila, Paivi S, Vaara, Ari T, von Smitten, Karl AJ, Vakkila, Jukka M, Leidenius, Marjut HK
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2009
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723126/
https://ncbi.nlm.nih.gov/pubmed/19604349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-231
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