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Quantifying the Relationships among Drug Classes

The similarity of drug targets is typically measured using sequence or structural information. Here, we consider chemo-centric approaches that measure target similarity on the basis of their ligands, asking how chemoinformatics similarities differ from those derived bioinformatically, how stable the...

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Detalhes bibliográficos
Main Authors: Hert, Jérôme, Keiser, Michael J., Irwin, John J., Oprea, Tudor I., Shoichet, Brian K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722950/
https://ncbi.nlm.nih.gov/pubmed/18335977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci8000259
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