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Eya1 gene dosage critically affects the development of sensory epithelia in the mammalian inner ear

Haploinsufficiency of the transcription co-activator EYA1 causes branchio–oto–renal syndrome, congenital birth defects that account for as many as 2% of profoundly deaf children; however, the underlying cause for its dosage requirement and its specific role in sensory cell development of the inner e...

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Hlavní autoři: Zou, Dan, Erickson, Christopher, Kim, Eun-Hee, Jin, Dongzhu, Fritzsch, Bernd, Xu, Pin-Xian
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722896/
https://ncbi.nlm.nih.gov/pubmed/18678597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn229
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