Dietary genistein negates the inhibitory effect of letrozole on the growth of aromatase-expressing estrogen-dependent human breast cancer cells (MCF-7Ca) in vivo

Genistein (GEN), a soy isoflavone, stimulates growth of estrogen-dependent human tumor cells (MCF-7) in a preclinical mouse model for postmenopausal breast cancer. Antiestrogens and aromatase inhibitors are frontline therapies for estrogen-dependent breast cancer. We have demonstrated that dietary G...

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Autors principals: Ju, Young H., Doerge, Daniel R., Woodling, Kellie A., Hartman, James A., Kwak, Jieun, Helferich, William G.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2008
Matèries:
Cancer Prevention
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722859/
https://ncbi.nlm.nih.gov/pubmed/18632754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn161
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