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Guggulsterone modulates MAPK and NF-κB pathways and inhibits skin tumorigenesis in SENCAR mice

Guggulsterone (GUG), a resin of the Commiphora mukul tree, has been used in ayurvedic medicine for centuries to treat a variety of ailments. Recent studies have suggested that GUG may also possess anticancer effects. In the present study, we show that GUG possesses antitumor-promoting effects in SEN...

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Hlavní autoři: Sarfaraz, Sami, Siddiqui, Imtiaz A., Syed, Deeba N., Afaq, Farrukh, Mukhtar, Hasan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722858/
https://ncbi.nlm.nih.gov/pubmed/18684729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn180
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