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Arsenite alters global histone H3 methylation

Arsenic (As) is a well-characterized human carcinogen but is generally not mutagenic. The evidence that As induces both loss of global DNA methylation and gene promoter DNA hypermethylation has suggested that epigenetic mechanisms may play an important role in As-induced carcinogenesis. In the prese...

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Autors principals: Zhou, Xue, Sun, Hong, Ellen, Thomas P., Chen, Haobin, Costa, Max
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722848/
https://ncbi.nlm.nih.gov/pubmed/18321869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn063
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