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Estrogen receptor beta (ERβ) subtype-specific ligands increase transcription, p44/p42 mitogen activated protein kinase (MAPK) activation and growth in human non-small cell lung cancer cells
In non-small cell lung cancer (NSCLC) cells, 17β-estradiol increases transcription, activates MAPK, and stimulates proliferation. We hypothesize that estrogen receptor β (ERβ) mediates these responses because it, but not ERα, is detected in our NSCLC cell lines. To test this, we determined the effec...
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Glavni autori: | , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2009
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2722836/ https://ncbi.nlm.nih.gov/pubmed/19460433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2009.05.004 |
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