Estrogen receptor beta (ERβ) subtype-specific ligands increase transcription, p44/p42 mitogen activated protein kinase (MAPK) activation and growth in human non-small cell lung cancer cells

In non-small cell lung cancer (NSCLC) cells, 17β-estradiol increases transcription, activates MAPK, and stimulates proliferation. We hypothesize that estrogen receptor β (ERβ) mediates these responses because it, but not ERα, is detected in our NSCLC cell lines. To test this, we determined the effec...

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Detalhes bibliográficos
Main Authors: Hershberger, Pamela A., Stabile, Laura P., Kanterewicz, Beatriz, Rothstein, Mary E., Gubish, Chris T., Land, Stephanie, Shuai, Yongli, Siegfried, Jill M., Nichols, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722836/
https://ncbi.nlm.nih.gov/pubmed/19460433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2009.05.004
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