pH Modulation of Efflux Pump Activity of Multi-Drug Resistant Escherichia coli: Protection During Its Passage and Eventual Colonization of the Colon

BACKGROUND: Resistance Nodulation Division (RND) efflux pumps of Escherichia coli extrude antibiotics and toxic substances before they reach their intended targets. Whereas these pumps obtain their energy directly from the proton motive force (PMF), ATP-Binding Cassette (ABC) transporters, which can...

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Main Authors: Martins, Ana, Spengler, Gabriella, Rodrigues, Liliana, Viveiros, Miguel, Ramos, Jorge, Martins, Marta, Couto, Isabel, Fanning, Séamus, Pagès, Jean-Marie, Bolla, Jean Michel, Molnar, Joseph, Amaral, Leonard
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722724/
https://ncbi.nlm.nih.gov/pubmed/19684858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006656
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