pH Modulation of Efflux Pump Activity of Multi-Drug Resistant Escherichia coli: Protection During Its Passage and Eventual Colonization of the Colon

BACKGROUND: Resistance Nodulation Division (RND) efflux pumps of Escherichia coli extrude antibiotics and toxic substances before they reach their intended targets. Whereas these pumps obtain their energy directly from the proton motive force (PMF), ATP-Binding Cassette (ABC) transporters, which can...

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Detalhes bibliográficos
Main Authors: Martins, Ana, Spengler, Gabriella, Rodrigues, Liliana, Viveiros, Miguel, Ramos, Jorge, Martins, Marta, Couto, Isabel, Fanning, Séamus, Pagès, Jean-Marie, Bolla, Jean Michel, Molnar, Joseph, Amaral, Leonard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722724/
https://ncbi.nlm.nih.gov/pubmed/19684858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006656
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