The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium

Cardiac sodium channels are responsible for conduction in the normal and diseased heart. We aimed to investigate regional and transmural distribution of sodium channel expression and function in the myocardium. Sodium channel Scn5a mRNA and Na(v)1.5 protein distribution was investigated in adult and...

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Detalhes bibliográficos
Main Authors: Remme, C. A., Verkerk, A. O., Hoogaars, W. M. H., Aanhaanen, W. T. J., Scicluna, B. P., Annink, C., van den Hoff, M. J. B., Wilde, A. A. M., van Veen, T. A. B., Veldkamp, M. W., de Bakker, J. M. T., Christoffels, V. M., Bezzina, C. R.
Formato: Artigo
Idioma:Inglês
Publicado em: D. Steinkopff-Verlag 2009
Assuntos:
Original Contribution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722719/
https://ncbi.nlm.nih.gov/pubmed/19255801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-009-0012-8
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