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Analysis of fine-scale mammalian evolutionary breakpoints provides new insight into their relation to genome organisation

BACKGROUND: The Intergenic Breakage Model, which is the current model of structural genome evolution, considers that evolutionary rearrangement breakages happen with a uniform propensity along the genome but are selected against in genes, their regulatory regions and in-between. However, a growing b...

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Detalhes bibliográficos
Main Authors: Lemaitre, Claire, Zaghloul, Lamia, Sagot, Marie-France, Gautier, Christian, Arneodo, Alain, Tannier, Eric, Audit, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722678/
https://ncbi.nlm.nih.gov/pubmed/19630943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-335
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